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Vaccines Development

Researchers' work adds to vaccines development body of knowledge

Published in Vaccine Weekly, October 12th, 2005

Vaccines development data are the focus of recent research from Australia, France and the United States.

Study 1: Scientists investigate ansB- and sspA-derived promoters for multi- and single-copy antigen expression in attenuated Salmonella enterica in a recent issue of Vaccine.

"Five candidate promoters were examined to determine their utility in directing immunogenic levels of expression of the C fragment from tetanus toxin in attenuated S. enterica used as an oral vaccine in mice. Promoters derived from the genes encoding the stringent starvation protein (sspA) from E. coli and S. enterica, but not ansB derived...

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