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Drug Development

Pivotal phase III trials of Japanese encephalitis vaccine begin

Published in Vaccine Weekly, October 12th, 2005

Intercell AG (VSE, ICLL) announced the start of global multicenter phase III clinical trials of its Japanese encephalitis vaccine, IC51.

Japanese encephalitis (JE) is a mosquito-borne flaviviral infection and the leading cause of viral encephalitis in Asia.

The infection is a major health problem throughout Asia where 3 billion people live in JE-endemic areas. A safe and efficacious traveler vaccine for tourists visiting Asian countries will meet a high unaddressed medical need. The global phase III program consists of a series of immunogenicity and safety trials, and will enroll more than 4900 subjects. Furthermore, a one time vaccination schedule...

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