HIV/AIDS Vaccine Development
SIVsm virus elicits antibodies with heterologous neutralizing activity
Published in Vaccine Weekly, October 26th, 2005
"We have evaluated the in a cohort of six Macaca nemestrina infected with the cloned virus SIVsm62d that showed different levels of envelope diversification. Two progressor macaques developed AIDS by 1.5 years post-inoculation and four non-progressors were asymptomatic for 3 years of follow-up. All macaques developed high titers of neutralizing antibodies against homologous SIVsm viruses and intermediate titers against SIVsmB670," scientists in the United States report.
"Heterologous virus...
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Source: Vaccine Weekly (2005-10-26)
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