Vaccine Weekly

Cancer Vaccine Development - Cancer immunotherapy targeting sperm protein 17 looks promising

Cancer Vaccine Development - Efficacy of cancer vaccine improved by manipulating cell trafficking

Leukemia - Benzodithiophenes induced differentiation and apoptosis in human leukemia cells

Multiple Sclerosis Vaccine Development - Highly immunogenic peptide vaccine for multiple sclerosis developed

Vaccine Policy - Immunocompetent travelers rarely require hepatitis A or B booster shots

Adverse Drug Reaction - Agencies issue alert on Menactra meningococcal vaccine and Guillain Barre syndrome

Adverse Drug Reaction - Physicians must be alert to severe adverse effects after vaccination

Alzheimer Disease - Anti-inflammatory therapies are good weapons in the fight against AD

Alzheimer Disease - Researchers sniff out a novel therapy for AD using compounds already in use

Anticancer Agents - Virgin olive oil phenols exert anticancer effects on colorectal carcinogenesis

Anticancer Drugs - TrxR inhibition contributes to cytotoxicity of anticancer compounds

Cancer Vaccines - Studies describe new findings in cancer vaccines research

Antitumor Drugs - In silico screening method identified potential antitumor drugs

Apoptosis - Adenosine analog induced cell cycle arrest and apoptosis in leukemia HL-60 cells

Apoptosis - Motexafin gadolinium induces caspase-dependent apoptosis

Apoptosis - Nitric oxide-donating NSAID, NCX 4040, exhibited pro-apoptotic effect

Apoptosis - Thiophene analogues of kenpaullone marked as possible anticancer drugs

Apoptosis - Water-soluble derivative of propolis influenced antitumor activity

HIV/AIDS Vaccines - Researchers' findings advance HIV/AIDS vaccines research

Argentine Hemorrhagic Fever - Researchers recommend use of Candid 1 vaccine in children under 15 years old

Atherosclerosis - CC-chemokine is a potential target for improving vein graft patency

Autoimmune Disease - Cytosolic adaptor protein required for proper activation of immune system

Biochemical Research - Adenovirus-mediated TPO gene transfer stimulates oval cell proliferation in liver

Biotechnology - Researchers seek lower raw material costs for intein purification processes

Bioterrorism - Proposal submitted to supply Imvamune smallpox vaccine to U.S. government

Bioterrorism - RiVax safe against ricin

Bioterrorism - U.S. NIH awards $4.6 million challenge grant for R&D of intranasal anthrax vaccine

Bladder Cancer Vaccine - Immunotherapy of prostate and bladder cancer reviewed

Blood Coagulation - VKORC1 is a key regulatory protein in synthesis of active vitamin K-dependent proteins

Breast Cancer - Nonmammary apomucins show a potential role in breast cancer glycoimmunology

Breast Cancer Vaccine - Antibody 5C3 recognizes heteropolymer of cytokeratin 9

Business Development - Discontinuation of Canvaxin trials leads to layoffs

Cancer Prevention - Vaccine prevented high-grade cervical precancers in phase III study

Cancer Research - Society awards $37.5 million in grants for research advancing blood cancer therapies

Cancer Therapy - Adriamycin delayed gross metastases from osteosarcoma

Cancer Therapy - Timetable changed for BLP25 liposome vaccine phase III trial

Cancer Therapy - Uracil-tegafur chemotherapy was not recommended

Cancer Vaccine Development - Best cancer vaccine releases hsp70 with chaperoned antigen and danger signal

Cancer Vaccine Development - DHBcAg is potent carrier protein for augmenting MUC1 antigenicity

Cancer Vaccine Development - Mechanism of anti-tumor immunity in mice vaccinated with fusion protein examined

Cancer Vaccine Development - New CTL epitopes and their agonist epitopes of mesothelin identified

Cancer Vaccine Development - T cell-mediated suppression of angiogenesis protects against tumors

Cancer Vaccines - Studies advance knowledge in cancer vaccines research

Chemotherapy - RMP-7 and carboplatin administration with radiotherapy deemed feasible

Cholera Vaccines - Reports describe recent advances in cholera vaccines research

Colon Cancer Vaccine Development - IL-8 preserves angiogenic response in HIF-1 alpha-deficient colon cancer

Cytomegalovirus - Deletion of gpUL132 is associated with a replication deficit

Dendritic Cell Vaccine - IL-12p70 production alone not sufficient to induce Th1 responses

Diagnostics - Multicolor flow cytometry provides phenotypic information on virus HA-specific B cells

Drug Development - DHA and 10-hydroxycamptothecin conjugate synthesized

Drug Safety - Healthcare providers notified of adverse events from Menactra meningococcal vaccine

Enteritis Vaccine - Subunit vaccine against hemorrhagic enteritis adenovirus developed

Epidemiology - Congo basin monkeypox more virulent for cynomolgus monkeys than West African monkeypox

Facilities - Life science engineering and consultancy company builds new vaccine facility for Bavarian Nordic

Fascioliasis - Fasciola antigens show promise as vaccines against fascioliasis and schistosomiasis

Finance - Pharmaceutical company raises GBP 750,000 for preclinical development of interferon alpha-8

Genital Herpes Vaccine - Majority of parents would allow children to be vaccinated against genital herpes

Geriatrics - Pneumococcal immunizations more likely in nursing homes with vaccine programs

Glaucoma Vaccine Development - Activation of extracellular signal-regulated kinase protects retinal ganglion cells

Glycogen Storage Disease - rAAV vectors mediate sustained therapeutic levels of correction of skeletal and cardiac muscles

Graves Disease - Animal models show light at end of tunnel in the fight for prevention of Graves disease in humans

HIV/AIDS Vaccine Development - U.S. NIH launches first phase II trial of HIV/AIDS vaccine

HIV/AIDS Vaccines - Research add new data to HIV/AIDS vaccines body of knowledge

Heart Attack - Increasing elastin within myocardial scars shows benefit

Hepatitis B Vaccine - Booster vaccination against hepatitis B not necessary for long-term protection