Vaccine Vector
Model for intracellular trafficking of adenoviral vectors developed
Published in Vaccine Weekly, November 2nd, 2005
According to recent research from the United States, "Here we develop an integrative computational framework to model biophysical processes involved in viral gene delivery. The model combines reaction-diffusion-advection equations that describe intracellular trafficking with kinetic equations that describe transcription and translation of the exogenous DNA. It relates molecular-level trafficking events to whole-cell distribution of viruses."
"The approach makes use of the current understanding of cellular processes and data from single-particle single-cell...
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Source: Vaccine Weekly (2005-11-02)
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