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Heart Attack

Increasing elastin within myocardial scars shows benefit

Published in Vaccine Weekly, November 2nd, 2005

Increasing elastin within myocardial scars after myocardial infarction reduces expansion and preserves ventricular function.

According to recent research from Canada, "After a myocardial infarction, the injured region becomes fibrotic and the myocardial scar may expand if the ventricular wall lacks elasticity. Cardiac dilatation may precipitate the vicious cycle of progressive heart failure."

T. Mizuno and associates at the University of Toronto explained, "The present study evaluated the functional benefits of increasing elastin within a myocardial scar using cell based gene therapy. A myocardial infarction was generated by ligation of the left...

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