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Clinical trial of antiviral HIV/AIDS therapeutic in HIV-positive patients initiated

Published in Vaccine Weekly, November 9th, 2005

Koronis Pharmaceuticals, Inc. announced the initiation of a phase 1b clinical trial of KP-1461, its anti-viral therapeutic, in HIV-positive patients.

The objectives of the trial are to evaluate the safety, toxicity, pharmacokinetic profile and initial clinical activity of KP-1461. The trial is being conducted at several HIV treatment centers in the United States.

KP-1461 is a first-in-class therapeutic designed to overcome the problem of drug resistance that has emerged with approved HIV treatments. KP-1461 has a novel mechanism of action designed to eliminate the human immunodeficiency virus (HIV) by selectively increasing its natural mutation rate...

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