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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . November 16th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Anthrax Vaccine Development - Monoclonal antibody protects against anthrax toxin

Atherosclerosis Vaccine Development - Chimeric enzyme vaccine attenuated atherosclerosis in rabbit model

Hookworm Vaccine Development - Hookworm heme-binding glutathione transferase has vaccine potential

Meningitis Vaccine Development - Anti-idiotypic antibody is candidate for meningitis vaccine

Vaccine Adjuvant -  Salmonella flagellin component potentiates immune responses

Allergy Medicine - Recent findings in allergy medicine provide new insights

Apoptosis - Alpha-tocopheryl succinate selectively induced apoptosis in neuroblastoma cells

Avian Influenza - Volunteers sought for avian flu vaccine study

Blood Safety - Blood screening and vaccines lower the risk of transfusion-transmitted infections in Italy

Botulinum Neurotoxin - Antibody response to receptor binding domain of botulinum serotypes examined

Cancer Therapy - Recent findings illuminate research in cancer therapy

Business & Finance - Avid Bioservices to provide development services for monoclonal antibody

Business & Finance - Genetics therapy-focused biotech company completes $30 million financing

Cancer Cell Inhibition - D-allose demonstrated inhibitory effect on cancer cell proliferation

Cancer Therapy - Butyrate regulates sphingomyelin in colon and liver cancer cells

Cancer Therapy - Findings advance knowledge in cancer therapy research

Cancer Therapy - Four diterpenoid inhibitors of Cdc25B phosphatase extracted from marine anemone

Cancer Vaccines - New findings in cancer vaccines described

Cancer Therapy - Growth inhibition activity of squamostolide evaluated

Cancer Therapy - LY293111 administered safely to patients with advanced solid tumors

Cancer Therapy - Target suppression and antitumor activity of MEK inhibitor CI-1040 demonstrated

Cancer Vaccine Development - Epitopes recognized by antibodies specific for tumor antigen NY-ESO-1 identified

Cancer Vaccine Development - Immunotherapy of glioblastoma multiforme stimulates CTL reaction

Cancer Vaccines - New findings in the area of cancer vaccines described

Cancer Vaccines - Findings describe new data in cancer vaccines research

Cancer Vaccines - New findings in the area of cancer vaccines detailed

Cancer Vaccines - Strategy for developing vaccine therapies for pediatric malignancies outlined

Chemotherapy - Bamet-UD2 overcomes resistance to cisplatin

Chemotherapy - Combination of oxaliplatin, leucovorin and fluorouracil deemed effective

Chemotherapy - Gemcitabine used in treatment of advanced head and neck cancer

Chemotherapy - Irinotecan plus temozolomide was well tolerated in malignant glioma patients

Cancer Vaccines - Reports describe recent advances in cancer vaccines research

Chemotherapy - Temsirolimus used to treat recurrent glioblastoma multiforme

Chemotherapy - Temsirolimus used to treat relapsed mantle cell lymphoma

Clinical Trials - DNA 'prime-boost' vaccine technology enters phase 2 clinical trial for HIV

Clinical Trials - Phase 2 testing of HIV vaccine developed with Vaccine Research Center initiated

Complementary & Alternative Medicine - Justicidin A induces apoptosis in human colorectal cancer cells

DNA Research - Mycobacteria Ag85B elicits effective CTL responses

Diabetes Vaccine Development - Glutamic acid decarboxylase peptide expands diabetogenic T cell clone

Infections - Research in infections provides new insights

Drug Delivery - Study: For injectable drug delivery, drug companies must keep both eyes on end user

Drug Development - Application filed with U.S. FDA for combined therapy for cancer treatment

Drug Development - Inhibition of matriptase prevents invasive growth of prostate and colon cancers

Drug Development - Phase I trial of AG-707 therapeutic vaccine for genital herpes initiated

Drug Development - Workshop proceedings discuss managing risks of therapeutic products

Facilities - Nabi completes $20 million Florida vaccine plant

Vaccines Delivery - Findings advance knowledge in vaccines delivery research

Gastric Cancer Vaccine - Ig superfamily 11 (IGSF11) is target for gastrointestinal and liver cancer

HIV/AIDS Diagnostics - Rapid test kit increases presence in South Africa; moves into East Africa

HIV/AIDS Therapy - AIDS Support Organization opens AIDS counseling and training center in Uganda

HIV/AIDS Therapy - Updated HIV guidelines support fusion inhibitor plus protease inhibitor therapy

HIV/AIDS Vaccine Development - CD8+ lymphocytes do not protect against acute SIV superinfection

HIV/AIDS Vaccine Development - HIV trials feasible with fewer animals if subjects repeatedly challenged with low doses

Vector Development - Reports describe recent advances in vector development research

HIV/AIDS Vaccine Development - HIV-1 Env clones developed for standardized assessments of vaccine-elicited neutralizing antibodies

HIV/AIDS Vaccine Development - Research collaboration formed to develop topical delivery of therapeutic DNA vaccines

Hepatitis A Vaccine - Havrix now approved for use in children aged 12 months and older

Hepatitis A Vaccine - U.S. CDC recommends that all children receive vaccinations for hepatitis A

Hepatitis B Vaccine - Alaska Natives immunized at birth are protected against hepatitis B

Hepatitis B Vaccine Development - Agreement signed to produce hepatitis B therapeutic vaccine candidate

Hepatitis B Virus - Vaccination reduces hepatitis B prevalence in U.S. children

Hepatitis C Vaccine - Spontaneous responders to hepatitis C viremia have expansive epitope recognition

Hepatitis C Vaccine Development - Epitope characterization paves the way for hepatitis C peptide-based vaccines

Infant Mortality - Vitamin A reduces infant deaths from measles, studies confirm

Infections - Findings in infections provide new insights

Infectious Diseases - Disease susceptibility to tuberculosis is dependent on host genetic predisposition

Influenza - Antivirals and vaccines maker offers pandemic flu plans

Influenza - Majority of Americans with asthma not immunized against flu despite known risks

Influenza Vaccines - Dutch company updates progress in scale-up of cell-culture-based influenza vaccine programs

Leukemia Vaccine Development - Acute promyelocytic leukemia cells cleared by adaptive immune mechanisms

Liver Cancer Vaccine Development - Autoantibodies against tumor-associated antigens in liver cancer identified

Lung Cancer - Camptothecin-somatostatin conjugates inhibit growth of lung cancer cells

Malaria Vaccine - Binding hot spot for invasion inhibitory molecules on P. falciparum antigen identified

Malaria Vaccine - Polymorphisms in malaria T cell epitopes not selected by immune pressure

Malaria Vaccine - Protective human immunity is a vaccine discovery tool for falciparum malaria

Malaria Vaccine Development - Changes in host cell tropism limits efficacy of malaria vaccine

Malaria Vaccine Development - Model system for testing malaria vaccines developed

Meningitis Vaccine Development - Meningococci from invasive meningococcal disease cases in Canada characterized

Mumps Vaccine - Plaque reduction neutralization is sensitive, specific for wild-type mumps virus

Pediatric Vaccine - Electronic registries may allow children to receive late routine vaccinations

Personnel - Therapeutic vaccine maker appoints management board for further growth

Pertussis Vaccine -  Bordetella parapertussis clearance from respiratory tract requires humoral and cellular immunity

Pertussis Vaccines - New research in the area of pertussis vaccines detailed

Pharmaceutical Research - RiVax maker provides business and clinical update; RiVax phase I trial complete

Pneumococcal Vaccines - Recent studies add new data to pneumococcal vaccines research

Pneumonia - Preventing pneumonia in children helps prevent pneumonia in older adults

Respiratory Papillomatosis Vaccine - Immune stimulation is not effective for treatment of papilloma

Rubella Vaccine - Complex regional pain syndrome type I reported after rubella vaccine

SARS - Reports advance knowledge in SARS research

Smallpox Vaccines - Reports describe recent advances in smallpox vaccines research

Staphylococcus Vaccine - Conjugate vaccine elicits antibodies that protect against S. aureus infection

Streptococcal Vaccine - Antibodies to iron uptake ABC transporter lipoproteins promote phagocytosis of Streptococcus

Streptococcal Vaccine Development - Prospects for group A streptococcal vaccine reviewed

Transplant Medicine - Recent findings illuminate research in transplant medicine

Vaccine Development - Recombinant antibody libraries aid vaccine research

Vaccine Development - Whooping cough vaccine is not just for kids anymore

Vaccine Efficacy - Pneumococcal vaccine likely to fail in splenectomized cancer patients

Vaccine Efficacy - UV radiation modifies leukocyte and cytokine responses to vaccination

Vaccine Research - New study shows measles immunization may prevent fatal brain infection

Vaccine Research - Pall Corporation presents approach for speeding vaccine production to Shanghai conference

Vaccine Safety - Data mining methods on the Vaccine Adverse Event Reporting System database compared

Vaccines Delivery - Data advance knowledge in vaccines delivery research

Vaccinia Virus - NK cell migration early after vaccinia infection characterized

Vaccinia Virus - PCR is most sensitive for vaccinia virus detection in patient specimens

Vector Development - Findings describe new data in vector development research

Virology - HIV and hepatitis C virus infection elicit similarities in natural killer cells

Virology - Researchers publish new studies and findings in the area of virology

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