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Drug Delivery

Zein microspheres show promise as drug/vaccine delivery vehicles

Published in Vaccine Weekly, November 30th, 2005

Zein microspheres show promise as vehicles for drug and/or vaccine delivery.

In a report published in the Journal of Drug Delivery Science and Technology, pharmacists in England described "the formulation of nonporous, spherical microspheres composed of zein (a protein from corn) for drug/vaccine delivery."

"Microspheres were prepared by a simple coacervation technique, and a factorial design was used to understand the effects of experimental variables on the particles formed," explained P. Hurtado-Lopez and coauthors at the University of London.

"Ovalbumin, as a model antigen, was loaded into zein microspheres with a...

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