Cancer Vaccine
Fusion protein vaccine generates potent antitumor effects
Published in Vaccine Weekly, November 30th, 2005
"Antigen-specific immunotherapy represents an attractive approach for cancer treatment because of the capacity to eradicate systemic tumors at multiple sites in the body while retaining the requisite specificity to discriminate between neoplastic and non-neophistic cells. It has been shown that certain domains of bacterial exotoxins facilitate translocation from extracellular and vesicular compartments into the cytoplasm. This feature provides an opportunity to enhance class I and/or II presentation of exogenous antigen to T...
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Source: Vaccine Weekly (2005-11-30)
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