Vaccine Weekly

Huntington Disease Vaccine - Anti-huntingtin shRNAs induce partial reversal of Huntington disease

Immunology - Live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profiles is developed

Influenza Vaccines - CombiMatrix and Novavax to collaborate on technology for influenza vaccine

Influenza Vaccines - Missed opportunities lead to low influenza immunization rates among children

Influenza Vaccines - Vaccination against influenza benefits cancer patients

Influenza Virus - Tangential flow filtration for influenza virus purification is described

Leishmaniasis Vaccine - Leishmune vaccine blocks transmission of canine visceral leishmaniasis

Leukemia - Findings advance knowledge in leukemia research

Leukemia Vaccine - Lentivirus conjugation to paramagnetic particles allows infection of leukemia cells

Malaria - Researchers' data advance malaria research

Malaria - Scientists find more evidence of resistance to once effective malaria drugs

Malaria Therapy -  P. falciparum gene contains sequences that are potential malaria targets

Malaria Vaccine - Follow-up study shows malaria vaccine effective over 18-month observation period

Meningitis Vaccines - New research in the area of meningitis vaccines detailed

Meningococcal Vaccine - Infant rat protection assay not sensitive enough to evaluate serogroup B vaccine responses

Meningococcal Vaccine - New meningococcal diphtheria toxoid conjugate vaccine is safe and immunogenic

Multiple Sclerosis - Study shows Rebif does not alter immune response to influenza vaccine

Mycobacteria Vaccine - Cellular immune responses to Mycobacterium avium paratuberculosis antigens characterized

Non-Hodgkin Lymphoma - Antibodies that neutralize complement-regulatory proteins control resistance in cancer

Orthopoxvirus Vaccine - Antipoxvirus compound protects mice from lethal orthopoxvirus challenge

Otitis Media Therapy - Updated clinical practice guidelines for acute otitis media are released

Ovarian Cancer - A-kinase anchoring protein mRNA expression linked to poor prognosis in epithelial ovarian cancer

Pertussis Vaccine - New pertussis vaccine has potential to prevent a million cases in adults, teens

Pneumococcal Disease - Prevalence of pediatric pneumococcal serotypes is increased in elderly

Polio Vaccine - Probiotic bacteria stimulate virus-specific antibodies after polio booster

Polio Vaccine - Vaccine-derived poliovirus excretor is found in Taiwan

Product Licensing - Agreement signed to license synthesized adjuvant from Eisai Co.

Prostate Cancer - Post-translational modifications of heat shock protein gp96 affect function

Prostate Cancer Vaccine - Anti-androgen plus vaccine therapy benefits prostate cancer patients

Prostate Cancer Vaccine - Human CTL epitopes may be candidates for prostate cancer immunotherapy

Protein Production - Flexible medium-throughput strategy for protein production is developed

Shigellosis Vaccine - Drug resistance prompts need for shigellosis vaccine in Thailand

Smallpox Vaccine - Doctors and public safety personnel need more information on smallpox vaccine

Smallpox Vaccine - Expedition to bring smallpox vaccine to New World and Asia in 19th century is outlined

Smallpox Vaccine - Measures taken to stockpile smallpox vaccine are reviewed

Smallpox Vaccine - T-bet required for protection against vaccinia virus infection

Streptococcal Vaccine - Immunoglobulin-binding protein protects against group A Streptococcus

Tetanus Vaccine - Attenuated immune response to tetanus toxoid in men is characterized

Toxoplasmosis Vaccine - NK cells induce CD8+ T-cell immunity against Toxoplasma in absence of CD4+ T cells

Tuberculosis Vaccine - Advances in adenovirus- and poxvirus-vectored TB vaccines are reviewed

Tuberculosis Vaccine - BCG revaccination does not reduce TB in school-aged children in Brazil

Tuberculosis Vaccines - New research in the area of tuberculosis vaccines detailed

Typhoid Fever - Drug resistance increases need for typhoid and paratyphoid fever vaccines

Vaccine Adjuvant - 2-Hydroxyethylmethacrylate has adjuvant properties in mice

Vaccine Delivery -  Yersinia vaccine carrier strains induce CD8+ T cell responses

Vaccine Delivery - DNA electrotransfer into skin using high- and low-voltage pulses is reported

Vaccine Delivery - Polymer-coated-bioadhesive liposomes are used as vaccine carriers

Vaccine Delivery - Suppressor T cells are induced through epicutaneous immunization

Vaccine Development - Peptide carrier with built-in vaccine adjuvant is developed

Vaccine Efficacy - TLR9 expression is linked to immune activation but impaired in chronic immune activation

Vaccine Safety - Information sought by callers to immunization hotline is discussed

Vaccine Vector - Conditional lethality yields new vaccine strain of Listeria monocytogenes

Vaccines Development - Recent findings in vaccines development provide new insights

Vector Development - HSV-1-derived vectors for gene transfer and gene therapy are reviewed

Vector Development - PEG conjugation protects adeno-associated viral vectors against antibody neutralization

Virology - Antiviral therapy and low-dose tricyclic antidepressants may help prevent postherpetic neuralgia

Virology - Recent studies add new data to virology research

Virology - Role of CD4+CD25+ regulatory T cells in viral infections is reviewed