Legionellosis Vaccine
Legionella pneumophila flagellum induces protective immunity
Published in Vaccine Weekly, December 7th, 2005
According to recent research published in the journal Vaccine, "The capacity of a purified preparation of Legionella pneumophila flagella (FLA) to induce protective immune responses was studied in an A/J mouse model. Animals immunized with FLA promptly mounted an anti-FLA antibody response and also developed a strong activation of both innate and adaptive cell-mediated immunity, as shown by an early release of pro-inflammatory cytokines in the peritoneal cavity, and by a positive cutaneous delayed-type hypersensitivity reaction and in vitro splenic lymphocyte...
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Source: Vaccine Weekly (2005-12-07)
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