Typhus Vaccine
Scrub typhus vaccine candidate induces immune responses in monkeys
Published in Vaccine Weekly, December 14th, 2005
According to recent research from the United States, "A truncated recombinant 56-kDa outer membrane protein of the Karp strain of Orientia tsutsugamushi (Kp r56) was evaluated in cynomolgus monkeys (Macaca fascicularis) for immunogenicity and safety as a vaccine candidate for the prevention of scrub typhus. This recombinant antigen induced strong humoral and cellular immune responses in two monkeys and was found to be well tolerated. Antigen-specific immunoglobulin M (IgM) and IgG were produced to almost maximal levels within one week of a single...
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Source: Vaccine Weekly (2005-12-14)
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