Cancer Therapy

Oncolytic viral therapy approved for head and neck cancer

Published in Vaccine Weekly, December 14th, 2005

Sunway Biotech Co., Ltd., announced that the Chinese State Food & Drug Administration (SFDA) has approved H101, an oncolytic adenovirus, to be used in combination with chemotherapy as a treatment for patients with late-stage refractory Nasopharyngeal cancer, a type of head and neck cancer prevalent in China.

According to the company, this marks the first oncolytic viral therapy approved by any regulatory agency in the world.

H101 is a modified adenovirus, a type of common cold virus found in most people. The deletion of an E1B-55kd segment in the virus results in its ability to selectively replicate in and kill tumor cells, while leaving normal cells...

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Source: Vaccine Weekly (2005-12-14)

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