Chemotherapy
Efficacy of cisplatin and platinum(IV) complexes unaffected by tumor microenvironmental factors
Published in Vaccine Weekly, December 14th, 2005
"The chemotherapeutic drug cisplatin is an important treatment for many types of solid tumors, in particular non-small cell lung cancer (NSCLC). Platinum(IV) complexes offer several advantages to cisplatin due to their requirement for reduction to the active platinum(II) form to elicit cytotoxicity," scientists in England reported.
"This should minimize non-specific effects and facilitate higher amounts of the active complexes reaching the target DNA. Hypoxia and a quiescent cell population are features of the tumor microenvironment known to lead...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
Source: Vaccine Weekly (2005-12-14)
More Articles from Vaccine Weekly
- E. Coli Vaccine
E. coli O157:H7 bacterial ghosts protect against lethal challenge - Influenza Vaccine
Sequencing of influenza reveals dynamic nature of viral genome evolution - Meningococcal Vaccine
LPS-based glycoconjugates prevent invasive meningococcal disease - Tobacco Use
Safe therapeutic vaccine for nicotine dependence has been developed - Tuberculosis Vaccine
Boosting with M. tuberculosis major secretory protein enhances BCG vaccine protection - Apoptosis
2-cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) induced apoptosis in pancreatic cancer - More from this issue of Vaccine Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
