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Influenza Vaccine

Sequencing of influenza reveals dynamic nature of viral genome evolution

Published in Vaccine Weekly, December 14th, 2005

The large-scale sequencing of human influenza revealed the dynamic nature of viral genome evolution.

According to a recent report from the United States, "Influenza viruses are remarkably adept at surviving in the human population over a long timescale. The human influenza A virus continues to thrive even among populations with widespread access to vaccines, and continues to be a major cause of morbidity and mortality. The virus mutates from year to year, making the existing vaccines ineffective on a regular basis, and requiring that new strains be chosen for a new vaccine. Less-frequent major changes, known as antigenic shift, create new strains against which the human...

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