Hepatitis B Vaccine
DNA vaccine adsorbed on microparticles enhances immune responses
Published in Vaccine Weekly, December 14th, 2005
"Plasmid expressing HBV small envelope antigen was formulated with poly(lactide-co-glycolide-acid) (PLGA) and cetyltrimethylammonium bromide (CTAB) to generate highly uniform microparticles. Controlled release of DNA from these microparticles was demonstrated in vitro and in vivo using flow cytometry and confocal laser scanning microscopy with the focus on localization and quantitatively evaluation of antigen-presenting cells (APCs) involved in the expression of target antigen," investigators in China report.
"Compared to mice vaccinated with...
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Source: Vaccine Weekly (2005-12-14)
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