Leukemia
Tamibarotene used to treat relapsed or refractory acute promyelocytic leukemia
Published in Vaccine Weekly, December 28th, 2005
"APL is a form of acute myeloid leukemia (AML) caused by a specific chromosomal translocation: t(15;17). This translocation creates a fusion between the promyelocytic (PML) leukemia gene and the retinoic acid receptor alpha (RAR alpha) gene to arrest the maturation of myeloid cells at the promyelocytic stage, leading to increased proliferation of promyelocytes," scientists reported in the journal Drugs of the Future.
"These accumulate in the bone marrow and peripheral blood, replacing normal blood cells. All-trans-retinoic acid (ATRA) therapy targets...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
Source: Vaccine Weekly (2005-12-28)
More Articles from Vaccine Weekly
- Malaria Vaccine Development
Nasal immunization with vaccine candidate prevents P. falciparum infection - Plague Vaccine
Vaccine induces cell-mediated protection against Yersinia pestis - Pneumonia Vaccine
Age-related changes occur in light-chain gene usage in response to pneumococcal polysaccharides - Vaccine Development
Vaccine development for immunosuppressed may be possible - Vaccine Vectors
Cross-species transfer of viruses has implications for live-virus vaccines - Adenovirus Vector
Innate immune response to adenovirus is reviewed - More from this issue of Vaccine Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
