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Measles Vaccine

Long-term immunity to measles virus is promoted by both Th1 and Th2 cells

Published in Vaccine Weekly, January 4th, 2006

Long-term immunity to measles virus may be promoted by both Th1 and Th2 cells.

"Immunity to measles is conferred by the interplay of humoral and cellular immune responses, the latter being critical in maintaining long-term recall response. Therefore, it is important to evaluate measles-specific humoral and cellular immunity in populations several years after vaccination and understand the correlations among these measures of immunity," according to scientists in the United States.

"We examined measles-specific antibodies, lymphoproliferation and the Th1/Th2 signature cytokines, interferon (IFN)-gamma and interleukin (IL)-4, in a population-based...

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