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Atherosclerosis Vaccine

Vaccine may enable immunomodulation of atherosclerosis

Published in Vaccine Weekly, January 11th, 2006

A vaccine based on apolipoprotein B100-related peptide could have a role in reducing atherosclerosis.

According to a report from the United States, "Experimental observations have established that the innate and adaptive immune mechanisms both have roles in the modulation of atherosclerosis. The complex function that the immune system has in the pathophysiology of atherosclerosis is highlighted by the fact that both pro-atherogenic and atheroprotective effects of immune activation can be demonstrated."

"An immune response to the protein and lipid components of oxidized LDL cholesterol has been observed in experimental models, and immunization with...

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