Human Papillomavirus Vaccine
Study characterized HPV-16 E6 DNA vaccines employing intercellular spreading strategies
Published in Vaccine Weekly, January 11th, 2006
According to investigators in the United States, "Human papillomavirus (HPV) E6 and E7 are consistently expressed and are responsible for the malignant transformation of HPV-associated lesions. Thus, E6 and E7 represent ideal targets for therapeutic HPV vaccine development."
"We have previously used the gene gun approach to test several intracellular targeting and intercellular spreading strategies targeting HPV-16 E7. These strategies include the use of the sorting...
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Source: Vaccine Weekly (2006-01-11)
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