Melanoma Vaccine
Fusion protein of IL-2 and diphtheria toxin does not eliminate regulatory T lymphocytes
Published in Vaccine Weekly, January 11th, 2006
According to recent research from the United States, "Elimination of regulatory T lymphocytes may provide a way to break self-tolerance and unleash the anti-tumor properties of circulating lymphocytes. The use of fusion proteins, which link cytotoxic molecules to receptor targets, provides one approach to this problem. This study examined the ability of a fusion protein of interleukin-2 (IL-2) and diphtheria toxin (Denileukin Diffitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes based on their expression of high-affinity IL-2...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
Source: Vaccine Weekly (2006-01-11)
More Articles from Vaccine Weekly
- Atherosclerosis Vaccine
Vaccine may enable immunomodulation of atherosclerosis - Diabetes Vaccine
DNA vaccine ameliorates type 1 diabetes in NOD mice - Meningitis Vaccine
Meningococcal C conjugate vaccine is immunogenic in preterm infants - Rotavirus Vaccine
Introduction of rotavirus vaccines is expected to substantially reduce mortality - Sepsis Vaccine
Detoxified endotoxin vaccine protects against lethal polymicrobial sepsis - Adeno-Associated Viral Vector
Efficient gene expression is produced by trans-splicing adeno-associated viral vectors - More from this issue of Vaccine Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
