Mucosal Immunization
Non-toxic enterotoxin-based chimeric protein induces immune memory
Published in Vaccine Weekly, January 11th, 2006
"Previous reports have suggested that peroral delivery of antigens chemically coupled to non-toxic recombinant enterotoxin B subunits, such as the cholera toxin B subunit (CTB), induces tolerance to the antigen that may be abrogated by the toxic enzyme activity of intact enterotoxins, such as cholera toxin (CT)," scientists in the United States report.
"The aim of this study was to examine the immunogenicity of a genetically coupled protein composed of the saliva-binding region (SBR) of the Streptococcus mutans surface antigen AgI/II and...
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Source: Vaccine Weekly (2006-01-11)
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