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West Nile Virus

West Nile vaccine begins Phase I clinical study

Published in Vaccine Weekly, January 18th, 2006

Dutch biotechnology company Crucell N.V. (CRXL) has obtained approval from Belgian authorities to test the safety, tolerability, and immunogenicity of its whole-inactivated West Nile virus vaccine in healthy volunteers. This opens the way for the imminent commencement of a Phase I clinical trial, with recruitment of volunteers underway.

The clinical trial for the human West Nile vaccine follows the June 2004 Israeli market authorization for a veterinary vaccine developed earlier together with the Kimron Veterinary Institute for use in geese. The first large commercial group of geese were recently vaccinated successfully at Kimron with two doses of the PER.C6(R)-based...

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