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Malaria Vaccine

 Plasmodium vivax MSP1 Pv200L is potential malaria vaccine subunit

Published in Vaccine Weekly, January 25th, 2006

Plasmodium vivax MSP1 Pv200L is a potential malaria vaccine subunit.

According to a study from Colombia, "The merozoite surface protein 1 (MSP-1) is expressed in all Plasmodium species and is considered a major malaria vaccine candidate. We found that MSP-1 from Plasmodium vivax (PvMSP-1) contains a region of significant sequence homology with the 190L subunit vaccine derived from the P. falciparum MSP-1."

"The fragment, termed Pv200L, was expressed as a recombinant protein in Escherichia coli (rPv200L) and used to asses its immunologic relevance as a vaccine target. A cross-sectional, sero-epidemiologic study...

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