Published in Vaccine Weekly, February 1st, 2006
Study 1: Small interfering RNAs show promise as a treatment for Huntington disease.
"Huntington disease (HD) is an autosomal dominant inheritable neurodegenerative disorder currently without effective treatment. It is caused by an expanded polyglutamine (poly Q) tract in the corresponding protein, huntingtin (htt), and therefore suppressing the huntingtin expression in brain neurons is expected to delay the onset and mitigate the severity of the disease."
"We have used small interfering RNAs (siRNAs) directed against the huntingtin gene to...
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