Susan Hasty, Publisher
Table of Contents . . . February 8th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Vaccine Weekly | Other Publications
Anthrax Vaccine - Anthrax spore vaccines based on toxin components have been developed
Chlamydia Vaccine - Vaccination of newborn mice protects against Chlamydia trachomatis
Diabetes Vaccine - Nasal vaccine against autoimmune diabetes has been developed
HIV/AIDS Vaccine - HIV-1 vaccine induces potent immune responses by needle-free intradermal delivery
Pertussis Vaccine - Study examined Bordetella pertussis antibody levels in children with asthma
Adenovirus Vector - Viral vector mitigates neutralization by antiviral antibodies
Allergy & Immunology - Immunotherapy for peanut allergy is getting closer to reality
Allergy & Immunology - Toll-like receptor ligands act as adjuvants in allergen-specific immunotherapy
Amyotrophic Lateral Sclerosis - Bcl-X L gene transfer is neuroprotective in models of motor neuron disease
Anthrax - Study shows no deaths in anthrax-infected animals when treated with BioThrax plus antibiotics
Atherosclerosis Vaccine - Apo B-100-related epitope reduces atherosclerosis and plaque inflammation
Avian Influenza - Bird flu infections in humans prompt new vaccine studies
Awards - U.S. NIH NIAID awards 2-year grant for development of influenza A virus vaccine
Bacteriology - Researchers determine a 'clonal' nature to Plasmodium falciparum
Bacteriology - Toll-like receptors are sentinels of host defense against bacteria
Baculovirus - Study characterized disassembly of structurally modified viral nanoparticles
Bordetella Vaccine - Mechanism of clearance of Bordetella from lungs requires TLR4
Breast Cancer - Epirubicin/paclitaxel compared with epirubicin/cyclophosphamide in breast cancer
Breast Cancer - Melatonin enhanced inhibitory effect of aminoglutethimide in breast cancer cells
Breast Cancer Vaccine - Livin may be a major breast cancer antigen
Cancer Therapy - Bioactive cyclic peroxides isolated from marine sponge Plakortis zyggompha
Cancer Therapy - Findings describe new data in cancer therapy research
Cancer Therapy - Novel benzopyridothiadiazepines identified as potential active antitumor agents
Cancer Therapy - Novel extracellular vesicles mediated anticancer drug resistance
Cancer Therapy - Novel flavonoid derivatives evaluated for anticancer activity
Cancer Therapy - Novel thermosensitive 5-fluorouracil-cyclotriphosphazene conjugates evaluated
Cancer Vaccines - Findings in cancer vaccines provide new insights
Cancer Vaccines - Researchers provide details of new studies and findings in the area of cancer vaccines
Cancer Vaccines - Researchers report details of new studies and findings in the area of cancer vaccines
Chickenpox Vaccine - Epidemiology of chickenpox is changing in Alberta
Chickenpox Vaccine - Lack of funding is limiting varicella vaccine coverage in Australia
Clinical Trials - Marketing application for investigational HIV protease inhibitor filed in Europe
Clinical Trials - Peg-Intron maintenance study in patients coinfected with hepatitis C and HIV initiated
Collaborations - Partnership signed to develop vaccine for hepatitis C
Contraceptive Vaccine - Adverse reactions to Freund's-adjuvanted immunocontraceptives were found in domestic cats
Cystic Fibrosis Therapy - Model for cystic fibrosis gene therapy has been developed
DNA Vaccine - CD4+ T cell-independent DNA vaccine shows promise against opportunistic infections
Dengue Vaccine - Recombinant yellow fever 17D-dengue type 2 virus shows promise for dengue fever vaccine
Diabetes Therapy - Hepatic insulin gene therapy prevents deterioration of vascular function
Diabetes Therapy - Researchers' data advance diabetes therapy research
Drug Development - Nitric oxide-donating aspirin induced apoptosis in human colon cancer cells
Drug Development - Sanofi pasteur makes milestone payment for bacterial vaccine development
Ebola Virus - Gene-specific therapies protect non-human primates from lethal disease
Finance - Biotech company closes $6 million financing and announces partnership for diabetes vaccine
Gastric Cancer - Anticancer drugs regulate peptide transporter 1 in gastric cancer cells
Gastric Cancer - ZD6474 inhibits gastric cancer tumor growth and intraperitoneal dissemination
Gene Delivery - Thermo-responsive polymers act as gene delivery vectors
Gene Delivery - Ultrasound is key factor in achieving nuclear DNA localization for gene delivery
Gene Therapy - AAV2/5-mediated NGF gene delivery protects septal cholinergic neurons following axotomy
Gene Therapy - Simian lentiviral vector provides stable transduction of monocytes
HIV/AIDS Prevention - Company signs partnership agreement with Clinton Foundation to supply HIV drugs
HIV/AIDS Prevention - Vaginal washing among African women increases risk of acquiring HIV-1
HIV/AIDS Testing - Developer announces selection of its HIV diagnostic test by Clinton Foundation
HIV/AIDS Therapy - IND for prevention of HIV receives fast tracks status from U.S. FDA
HIV/AIDS Vaccine - Cells from lentiviral-transduced CD34+ cells inhibited SHIV virus replication
HIV/AIDS Vaccine - Coreceptor-based anti-HIV strategy suppressed multiclade HIV-1 infections
HIV/AIDS Vaccine - HIV peptides in PLG microparticles enhance mucosal and systemic immune responses
HIV/AIDS Vaccine - Lack of awareness must be addressed to ensure adequate number of vaccine trial volunteers
HIV/AIDS Vaccine - Plasmid DNA and adenovirus vector with type 35 fiber protects against HIV
HIV/AIDS Vaccines - Recent studies add new data to HIV/AIDS vaccines research
HIV/AIDS Vaccines - Studies advance knowledge in HIV/AIDS vaccines research
Haemophilus Vaccine - Hib conjugate vaccine is less effective in HIV-infected African children
Head & Neck Cancer - Studies add new findings to head & neck cancer body of knowledge
Healthcare Coverage - New study finds employers fail to make cost-effective healthcare choices
Immunology - Cross-linking is needed for T cell co-stimulation activity of trimeric CD137L
Infectious Diseases - New web resource provides access to global health data by country and region
Infectious Diseases - Previous smallpox vaccination not associated with monkeypox disease severity
Influenza Vaccine - Adverse events are more likely when influenza vaccine is used inconsistent with labeling
Influenza Vaccine - GlaxoSmithKline biologicals submits first European pandemic influenza vaccine application
Influenza Virus - Report outlines EU regulations for eradication and control of poultry diseases
Leishmaniasis Vaccines - Findings describe new data in leishmaniasis vaccines research
Leukemia - Multiple myelomas and myeloid leukemias were sensitive to proteasome inhibitor I
Leukemia - Quercetin and trichostatin A exhibited cytotoxic effects in human leukemia cells
Liposomes - pH-sensitive peptide improves transfection efficiency of liposomes
Lung Cancer - Diallyl disulfide induced apoptosis in human A549 lung carcinoma cells
Lung Cancer - Docetaxel used to treat advanced non-small cell lung cancer
Lung Cancer - Gemcitabine compared to gemcitabine/carboplatin in non-small cell lung cancer
Lung Cancer - Safrole oxide induced apoptosis in A549 human lung cancer cells
Lung Cancer - Sesquiterpene lactones showed cytotoxicity against small cell lung cancer cell
Melanoma Vaccine - Study finds evidence for immunological tolerance against authochthonous melanomas
Melanoma Vaccines - Research in melanoma vaccines provides new insights
Meningitis Vaccine - Analysis of Neisseria meningitidis isolates reveals strains related to hypervirulent lineages
Meningitis Vaccine - Serogroup B Neisseria meningitidis vaccines are focus of review
Moneypox Risk Factors - Clinical characteristics of human monkeypox are the focus of review
Multiple Sclerosis Therapy - Inhibitor of alpha4 integrin suppressed allergic encephalomyelitis
Outbreak - Limited measles outbreak is reported in highly vaccinated U.S. boarding school
Pancreatic Cancer - Proteasome inhibitor MG132 induced apoptosis in human pancreatic cancer cells
Patents - U.S. patents granted relating to electroporation-enabled delivery of therapeutic molecules
Pediatric Vaccine - High proportion of children in Germany do not have adequate vaccine protection
Personnel - Dr. Raman Bedi joins oral healthcare company as senior consultant
Personnel - Pharmaceutical company appoints Matthew A. Wikler as chief medical officer
Pertussis Vaccine - Toxin inhibits neutrophil recruitment to delay B. pertussis clearance
Pharmaceutical Research - Center of Excellence in Infectious Disease and Biodefense launched
Pharmaceutical Research - Pharmacological study of tipifamib in advanced solid tumors conducted
Pneumococcal Vaccine - Invasive pneumococcal disease is declining in U.S. elderly
Pneumonia - Antibiotic resistance is returning pneumonia to a public health concern
Public Health - Monkeypox has re-emerged in the United States
Rabies Vaccine - Space-time cluster of adverse events is associated with canine rabies vaccine
Rectal Cancer - Oxaliplatin, capecitabine and external beam radiotherapy used in rectal cancer
Respiratory Syncytial Virus - Influenza isn't the only germ threat in winter
Rotavirus - Promise of Rotarix rotavirus vaccine discussed in major journal
Rotavirus - Published study finds Rotarix is effective against rotavirus disease in first year of life
Rotavirus - Vaccine prevented 98% of severe rotavirus gastroenteritis in infants
Rotavirus Vaccine - No link was found between rotavirus vaccine and intussusception in Honolulu
Rubella Vaccine - Matrix models for childhood infections have been applied to rubella and mumps
Smallpox Vaccine - Modified vaccinia virus Ankara protein acts with viral protein to block apoptosis
Smallpox Vaccine - Report describes adverse events linked to smallpox vaccine in U.S.
Smallpox Vaccine - Smallpox fusion proteins cross-react with neutralizing antibodies
Smallpox Vaccine - Vaccinia K1L protein mediates host-range function in RK-13 cells via ankyrin repeat
Tick-Borne Disease - Tick antigen vaccine controls Ixodes scapularis adult infestations
Tuberculosis Vaccine - BCG vaccine causes changes in peripheral blood T cell numbers in infants
Tuberculosis Vaccine - DNA vaccines against TB elicit efficient, protective immune responses
Tuberculosis Vaccine - Frequency of IFN-gamma-producing cells correlates with adjuvant enhancement of BCG vaccine
Tuberculosis Vaccine - Researchers examine strain-specific mycobacterial lipids and immunity to TB
Tuberculosis Vaccine - Vaccine induces cytokine responses in guinea pig model of pulmonary TB
Tuberculosis Vaccines - Recent findings illuminate research in tuberculosis vaccines
Typhoid Vaccine - Chinese typhoid vaccine appears effective
Vaccine Adjuvant - Low-toxicity MPL and RC529 are efficient adjuvants for CD4+ T cells
Vaccine Adjuvant - Melatonin finds use as vaccine agent
Vaccine Adjuvant - Rb1 fraction of ginseng elicits balanced Th1 and Th2 immune response
Vaccine Development - Mucosal effector memory T cells are focus of review
Vaccine Efficacy - Mucosal vaccines are improved by induction of innate immunity
Vaccine Efficacy - Report focuses on maximizing statistical power in group-randomized vaccine trials
Vaccine Vector - Method is developed to produce pseudotyped rAAV vectors using baculovirus expression system
Vaccine Vector - Study examined osmolality effect of serum-free media upon adenovirus production
Vaccines Vector - Studies advance knowledge in vaccines vector research
Vaccinia Virus Vaccine - Study examined substrate specificity of vaccinia virus thymidylate kinase
Vector Development - HSV-1 thymidine kinase delivered by HIV-based virus-like particles induced cell death
Vector Development - Polyomavirus EGFP-pseudocapsids introduce proteins and peptides into mammalian cells
Vector Development - Stable transgene expression is driven by promoter in HSV-1 vector
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