Published in Vaccine Weekly, February 8th, 2006
"Mucosally induced tolerance is an attractive strategy for preventing or reducing autoimmune diseases. We produced a recombinant CTB fusion protein linked with autoantigen T cell epitope of insulin B chain peptide 9-23 (C19S) at levels up to 200 mg/L culture media in Brevibacillus choshinensis secretion-expression system," researchers writing in the journal Biotechnology and Bioengineering report.
"Receptor-competitive assay showed...
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