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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . February 15th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Alzheimer Disease Vaccine - Study examined effects of epitopes and adjuvants on anti-Alzheimer DNA vaccine

Avian Influenza Vaccine - Research quantifies vaccination effect on transmission of avian influenza in chickens

Diabetes Vaccine - DNA vaccine prevents diabetes through enhanced beta cell proliferation

Herpes Vaccine - CpG ODN enhances HSV DNA vaccine efficacy against genital herpes

Vaccine Adjuvant - Vesiculated alpha-tocopheryl succinate enhances effect of dendritic cell vaccines

Addiction Medicine - Review examines future advances in addiction treatment

Adenovirus Vector - Scientists generated rabbit VH domain antibody specific to c-Met and adenoviral knob protein

Brain Tumor - Restoring neurogenesis might treat cognitive sequelae of brain tumor therapy

Breast Cancer - Spleen tyrosine kinase mediated breast tumor suppression

Breast Cancer Vaccine - ST6GalNAc I expression in breast cancer cells enhances tumorigenicity

Cancer Drugs - Cytotoxicity of MDL 72527 demonstrated in cancer cells

Cancer Drugs - Recommended dose of irinotecan in pediatric cancer patients announced

Cancer Inhibition - Polymeric polyphenols inhibited hematologic tumor cell lines

Cancer Therapy - Antiproliferative and apoptosis-inducing activity of Brucea javanica shown

Cancer Vaccine - Dendritic cell therapy with IFN-alpha suppresses tumors in colorectal cancer

Cancer Vaccine - Gastric cancer cell-dendritic cell hybrids induce tumor-specific T cells

Cancer Vaccine - Melanoma patient has spontaneous CTL response to MAGE-A3 peptide

Cancer Vaccine - NKT lymphocytes confer immunity via tumor-capturing dendritic cells

Cancer Vaccine - Report summarizes European Conference on Progress in Vaccination Against Cancer

Cancer Vaccines - New data illuminates research in cancer vaccines

Cancer Vaccines - Researchers detail new studies and findings in the area of cancer vaccines

Cervical Cancer - HPV typing from paraffin-embedded sections of cervical cancers deemed feasible

Cervical Cancer Vaccine - Study examined pediatricians' intention to administer HPV vaccine

Cervical Cancer Vaccine - Transcutaneous immunization protects against HPV-induced tumors

Clinical Trials - Cocaine vaccine prevents cocaine from getting out of the blood stream

Clinical Trials - Japanese encephalitis vaccine found to be safe in international phase 3 trials

Colon Cancer - Use of artepillin C helps prevent colon cancer

Complementary & Alternative Medicine - Anti-inflammatory potential of Antrodia camphorata demonstrated

Complementary & Alternative Medicine - Blueberry flavonoids inhibited MMP activity in DU145 human prostate cancer cells

Contraceptive Vaccine - Recombinant sperm protein shows promise for contraceptive vaccine

Cytomegalovirus - Study identified protein containing antigenic domain of cytomegalovirus glycoprotein B

DNA Vaccine - Method is developed for topical application of plasmid DNA to human skin

Diagnostics - Standard anti-Tn antibodies and lectins have unexpected cross-reactivity

Drug Resistance - Transcription factors and drug resistance discussed

Familial Amyloidotic Polyneuropathy - Y78F TTR mutant counteracts deposition in familial amyloidotic polyneuropathy

Foot-and-Mouth Disease - Analysis characterized viruses from 1993 Italian foot-and-mouth disease outbreak

Gastrointestinal Stromal Tumor - STI571 was effective treatment for gastrointestinal stromal tumor

Gene Therapy - Transduction of dendritic cells is enhanced by adeno-associated virus

Glaucoma Vaccine - T-cell-based vaccine to reduce intraocular pressure is under development

Gynecological Cancer - Nedaplatin exhibited strong antitumor activity in gynecological carcinomas

HIV/AIDS Research - Pharma companies select two next generation HIV fusion inhibitor drug candidates for development

HIV/AIDS Vaccine Trials - European commission recommends criteria for European and African HIV/AIDS vaccine trials

HIV/AIDS Vaccines - Findings advance knowledge in HIV/AIDS vaccines research

HIV/AIDS Vaccines - Reports add new data to HIV/AIDS vaccines research

HIV/AIDS Vaccines - Researchers describe findings in HIV/AIDS vaccines studies

Head & Neck Cancer - Carboplatin and raltitrexed used to treat head and neck squamous cell carcinoma

Hepatitis C Virus - T-cell responses against immunodominant HCV epitopes aid viral clearance

Immunology - Both MARCO and SR-A may be involved in positioning and differentiation of macrophages

Immunology - Immune system response to viral DNA differs from RNA virus recognition

Immunosuppression - Overstimulated immune cells lose their protective ability

Influenza - Fewer than half of U.S. healthcare workers get flu shots

Influenza - Scientists unravel critical genetic puzzle for flu virus replication

Influenza Vaccine - Nucleoprotein vaccine protects against multiple influenza subtypes

Influenza Vaccine - Universal influenza immunization is cost-effective in children 6 - 23 months old

Interleukin-2 - Interleukin-2 acts differently in primary and secondary HIV immunizations

Interleukin-2 - Regulatory T cell depletion enhanced vaccine-mediated immunity in cancer patients

Leukemia - Research in leukemia provides new insights

Leukemia - Researchers publish new studies and findings in the area of leukemia

Leukemia - TRAIL proposed as anticancer agent in acute myeloid leukemia

Liposomal Delivery - Study characterized adjuvant inducing cell-mediated immunity and antibody responses

Lung Cancer - Indian herbal medicine used to treat lung cancer

Lung Cancer - Topotecan/ifosfamide used to treat patients with platinum refractory lung cancer

Malaria - Plasmodium parasites found developing in lymph nodes

Malaria Vaccines Development - New findings in malaria vaccines development described

Measles Virus - Study examined significance of HLA class I genes in measles cytokine responses

Medical Devices - Qscan-Vaers available for vaccine adverse event reporting

Meningitis Vaccine - Unlabeled adverse effects linked to meningitis C vaccine were mostly minor

Meningitis Vaccines - Researchers detail new studies and findings in the area of meningitis vaccines

Mergers & Acquisitions - Biotech company acquires Serotec Group to strengthen global research antibody business

Non-Hodgkin Lymphoma - Vaccine boosts survival in patients with aggressive non-Hodgkin lymphoma

Oral Cancer Vaccine - DNA vaccine is effective against oral papillomavirus-linked oral cancer

Ovarian Cancer - NH2-terminally truncated p73 isoforms predicted poor prognosis in ovarian cancer

Patents - U.S. patent application filed for synDNA vaccines and other therapeutic compounds

Pediatric Vaccine - Model examines parental beliefs about child immunizations

Pediatric Vaccine - Report describes mothers' attitudes to childhood immunization in England

Personnel - Pharma company appoints Jeff Himawan to board of directors

Pneumonia - Study examined trends in hospitalization for pneumonia among elderly in U.S.

Product Licensing - Genmab licenses cell line standard for drug in vitro consistency studies

Prostate Cancer Vaccine - Docetaxel does not diminish effect of gonadotropin-releasing hormone vaccine in prostate cancer

Protein Expression - Screening system for expression profiling of virus proteins has been developed

Receptor Studies - TLR3 is highly expressed in inflammatory and HIV myopathies

Rheumatoid Arthritis - Cell therapy company acquires autologous T cell vaccine rights for rheumatoid arthritis

Ricin Vaccine - RiVax milestone achieved

Rotavirus Vaccine - Standardized approaches to monitor rotavirus vaccines are needed

Salmonella Vaccine - Vaccine protects against non-host-specific Salmonella serotypes in poultry

Smallpox - Studies in mice show potential of antibodies from chimps and humans to protect against smallpox

Smallpox Vaccine - Review examines neurologic adverse events linked to smallpox vaccine in U.S.

Smallpox Vaccine - Study characterized vaccinia virus antigens recognized by vaccinia immune globulin

Thyroid Cancer - Vitamin D3 therapy used to treat locally advanced thyroid cancer

Vaccine Delivery - Inorganic materials for gene-based nano-medicine delivery are focus of review

Vaccine Delivery - Report describes toxicity, tissue distribution of magnetic nanoparticles in mice

Vaccine Delivery - Review describes recent advances in lipid molecular design

Vaccine Delivery - Review examines chromosome engineering for delivery of therapeutic genes

Vaccine Delivery - Review examines nanotechnology for drug and gene therapy

Vaccine Delivery - Study examined delivery of ODN into saphenous veins and adjunct effect of ultrasound

Vaccine Development - Catalytic antibodies and their applications are focus of review

Vaccine Development - Rabies virus G-ERA-mediated apoptosis may help improve live vaccine immunogenicity

Vaccine Efficacy - Complement component C3d-antigen complexes can augment or inhibit humoral immunity

Vaccine Efficacy - Different subsets of skin migratory dendritic cells elicit CD4+ T cells

Vaccine Efficacy - Malaria chemoprophylaxis does not impair response to measles and DPT vaccines

Vaccine Efficacy - Use of vaccines in adult patients with renal disease is focus of review

Vaccine Safety - Aluminum granuloma is reported at injection sites after vaccination

Vaccine Vector - Adenovirus vector-incorporating antibody achieves targeted gene delivery

Vector Development - Antigen-presenting cells in CNS are targeted using hematopoietic stem cells

Vector Development - Findings advance knowledge in vector development research

Vector Development - Report describes production scale-up of packaging cell clearance of retroviral vector stocks

Vector Development - Trophic activity of rabies equine infectious anemia viral vector mediates neuron gene transfer

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