Published in Vaccine Weekly, February 15th, 2006
"A major challenge for the development of an effective HIV vaccine is to elicit neutralizing antibodies against a broad array of primary isolates. Monomeric gp120-based vaccine approaches have not been successful in inducing this type of response, prompting a number of approaches designed to recreate the native glycoprotein complex that exists on the viral membrane."
"Gag-Env pseudovirions are noninfectious...
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