Influenza Vaccines
Modified surfactant stimulates IgA in response to influenza antigen
Published in Vaccine Weekly, March 1st, 2006
According to recent research from Japan, "The intranasal administration of influenza hemagglutinin (HA) vaccine with Surfacten, a modified pulmonary surfactant free of antigenic c-type lectins, as a mucosal adjuvant induced the highest protective mucosal immunity in the airway. The intranasal immunization of mice with HA vaccine (0.2 mcg)-Surfacten (0.2 mcg) selectively induced the neutralizing anti-HA IgA, but not IgG, and conferred nearly maximal protection in the airway, without inducing a systemic response."
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Source: Vaccine Weekly (2006-03-01)
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