Susan Hasty, Publisher
Table of Contents . . . March 8th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Vaccine Weekly | Other Publications
Cancer Vaccine - Anti-tumor DNA vaccines protect against tumor development
Herpesvirus Vaccine - HF10 lacks neuro-invasiveness and protects against herpes simplex virus
Plague Vaccine - Flagellin is effective adjuvant against Yersinia pestis
Smallpox Vaccine - Deletion of gene A41L enhances vaccinia virus vaccine efficacy
Allergy & Immunology - T-cell reaction indicates response to Th1-adjuvanted allergy vaccine
Alzheimer Disease Vaccine - Anti-A-beta-specific mAbs attenuate amyloid deposition in Alzheimer disease
Anthrax Vaccines - New data illuminates research in anthrax vaccines
Apoptosis - Intraperitoneal PTD-BIR3-RING inhibits apoptosis in ischemic brain
Avian Influenza - Technology for accelerating development of H5N1 flu vaccine enters pilot study
Bacteremia - Vaccine urgently needed for lethal bacterial disease
Bacteriology - Recent findings in bacteriology described
Bioterrorism - Multiferon antiviral studies with U.S. Army researchers using alpha interferon reported
Bioterrorism - Smallpox therapy development underway by BioFactura at University of Maryland bioprocess facility
Bladder Cancer - Bladder cancer inhibited by 1,1-bis(3'-indolyl)-1-(P-substitutedphenyl)methanes
Bladder Cancer - Histone deacetylase inhibitors modulate sensitivity of TRAIL-resistant bladder tumor cells
Breast Cancer - Anandamide inhibited adhesion and migration of breast cancer cells
Breast Cancer - Idarubicin displayed cytotoxic effect on breast cancer multicellular spheroids
Breast Cancer - Orathecin exhibited minimal clinical benefit in metastatic breast cancer
Breast Cancer - Reports advance knowledge in breast cancer research
Business Update - Immuno-pharmaceutical company targeting MS, HIV therapies announces new business strategy
Cancer Therapy - Antitumor benzothiazoles showed inhibitory activity against cancer cell lines
Cancer Therapy - COX-2 inhibition augments the efficacy of a cancer vaccine
Cancer Therapy - Irofulven cytotoxicity characterized in human cancer cells
Cancer Therapy - Method optimizes modification of carrier proteins with aminated haptens
Cancer Therapy - Studies add new findings to cancer therapy body of knowledge
Cancer Therapy - Tiron identified as bortezomib blocker
Cancer Vaccine - Antitumor efficacy of CD137 ligation is maximized by tumor vaccine
Cancer Vaccine - Chimeric DNA vaccine reverses morphine-induced immunosuppression and tumorigenesis
Cancer Vaccine - Commercial launch of telomerase-immortalized cell line through ATCC announced
Cancer Vaccine - H-2Db-specific CD8+ T-cell epitopes inhibit tumor growth
Cancer Vaccine - IL-2/liposome potentiates immune responses to cancer vaccine
Cancer Vaccine - Therapeutic cancer vaccines amplify tumor-specific regulatory T cells
Cancer Vaccine - Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses
Cancer Vaccines - Recent studies add new data to cancer vaccines research
Cervical Cancer - Gardasil, a cervical cancer vaccine, to receive priority review from the U.S. FDA
Cervical Cancer Vaccine - DNA vaccines carrying HPV16 E7 peptide protect against cervical tumors
Chagas Disease - Metacaspases of Trypanosoma cruzi are candidates for apoptosis mediators
Cholera Vaccine - Peptides mimicking Vibrio cholerae capsular polysaccharide elicit protective antibody response
Clinical Trials - HIV/AIDS vaccine trial launched in Entebbe, Uganda, as three-way collaborative effort
Collaborations - India-based pharma company enters joint venture to market antiretroviral products in South Africa
Colon Cancer - Effect of indomethacin on E-cadherin and beta-catenin expression in colon cancer studied
Colon Cancer - Induction of oxidative metabolism by mitochondrial frataxin may inhibit cancer growth
Colon Cancer - Oral uracil/ftorafur plus leucovorin treated metastatic colorectal cancer
Complementary & Alternative Medicine - Hydroxyanthraquinone compounds exhibited cancer inhibitory activity
Complementary & Alternative Medicine - Tuber lectin extract showed anti-cancer effect on human cancer cell lines
Contraceptive Vaccines - Researchers publish new studies and findings in the area of contraceptive vaccines
Drug Delivery - Transdermal drug delivery company introduces next generation skin permeation device
Drug Development - Dasatinib may affect neoplasms associated with gain-of-function KIT mutations
Drug Development - Novel inhibitors of B-RAF based on a disubstituted pyrazine scaffold developed
Drug Development - Phase I/II trial of typhoid fever vaccine initiated
Drug Resistance - Role of gamma-glutamyltransferase expression in cancer cells and drug resistance explored
Finance - Biotech company reports 2005 financial results
Finance - Collaboration with VRA expanded to include preliminary development of an influenza vaccine
Finance - Human therapeutics company reports stockholder loss of $18.6 million, or $0.52 per share
Food Safety - Project focuses on vaccines, tests for infectious animal diseases in food supply
Food Safety - Report describes Salmonella survey of Japanese layer farms
Foot-and-Mouth Disease Vaccine - Fungus extract enhances immunogenicity elicited by foot-and-mouth disease vaccine
Gastric Cancer - Biweekly irinotecan and cisplatin found effective in treating advanced gastric cancer
Gene Therapy - Reports advance knowledge in gene therapy research
Glioma Vaccine - EGFRvIII-derived CTL epitopes restricted by HLA A0201 are identified for glioma immunotherapy
Gliomas - Trichostatin A could be used to achieve tumor growth inhibition and cytotoxicity of gliomas
HIV/AIDS Diagnostics - Diagnostic tests company upgrades dry filter spot HIV-1 collection solution to monitor viral load
HIV/AIDS Research - New research reaffirms ability of TNX-355 to block HIV-1
HIV/AIDS Research - Study shows HIV patients respond well to Reyataz therapy
HIV/AIDS Therapy - Drug compound kills multiple HIV strains in in vitro lab test, researchers report
HIV/AIDS Vaccine - Replication-defective viruses safe and efficient for vaccines and vaccine vectors
HIV/AIDS Vaccine - Vaccination with adenovirus vectors elicited broad immunity to SIV
HIV/AIDS Vaccines - Reports add new data to HIV/AIDS vaccines research
HIV/AIDS Vaccines - Researchers publish new studies and findings in the area of HIV/AIDS vaccines
HIV/AIDS Vaccines - Studies advance knowledge in HIV/AIDS vaccines research
Hepatitis C Virus - HCV NS3 protein protects dendritic cells from recombinant virus expressing NS3
Hepatitis C Virus - HCV affects dendritic cell cytokine induction and T-cell stimulation
Human Papillomavirus Vaccine - Cervical mucosal antibodies protect against human papillomavirus 16
Human Papillomavirus Vaccine - HPV type 6 L2E7 vaccine fails to increase efficacy of conventional therapy
Human Papillomavirus Vaccine - HPV-16 peptide-specific immune responses reduce recurrence of cervical intraepithelial neoplasia
Human Papillomavirus Vaccine - Pap test results predict HPV status in young women
Influenza - Australian firm to apply for license to market influenza vaccine in the U.S.
Influenza - Blue Cross and Blue Shield of Florida offers influenza shots to seniors
Influenza Vaccine - New influenza vaccine takes weeks - not months - to mass produce
Influenza Vaccine - New recommendations take aim to improve influenza vaccination rates among healthcare workers
Influenza Vaccine - Vaccination against influenza in rheumatoid arthritis was not affected by disease-modifying drugs
Legal Issues - Fluvirin maker announces termination of SEC investigation
Leishmaniasis Vaccine - Leishmania antigens that stimulate cellular immune responses have been identified
Leukemia - Combined treatment with BB-1 and TRAIL proposed as new cancer therapy strategy
Leukemia Vaccines - New findings in the area of leukemia vaccines described
Liver Cancer Vaccine - Dendritic cell vaccine and IL-12 result in autoimmune hepatic inflammation
Lung Cancer - Gemcitabine and cisplatin found effective in treating elderly patients with lung cancer
Lung Cancer - Gemcitabine used as first and second-line chemotherapy of lung cancer
Lung Cancer - Monitoring circulatory TBARs and SB could help prognosticate lung cancer
Lung Cancer Vaccine - Epidermal growth factor receptor induces T cell responses against lung cancer
Lymphoma - Phosphatidylinositol-3 kinase/Akt inhibition promoted apoptosis in Hodgkin lymphoma
Lymphoma Vaccine - IL-15 does not enhance efficacy of T cell lymphoma vaccine
Malaria Vaccines - Recent findings illuminate research in malaria vaccines
Malaria Vaccines - Reports add new data to malaria vaccines research
Malaria Vaccines - Researchers describe findings in malaria vaccines studies
Malaria Vaccines - Studies advance knowledge in malaria vaccines research
Medulloblastomas - Antiproliferative and radiosensitizing effects of CAPE for medulloblastoma shown
Melanoma - Paclitaxel and carboplatin were combined to treat metastatic melanoma
Melanoma Vaccine - Listeria vaccine elicited central nervous system tumor immunity
Melanoma Vaccine - Allogeneic whole-cell tumor vaccine expressing xenogeneic gp100 has been developed
Melanoma Vaccine - CCL21 adjuvant enhances immunogenicity of DNA melanoma vaccine
Melanoma Vaccine - Dendritic cell vaccine induces CD8+ T cell responses against NA17-A2 tumor peptide
Melanoma Vaccines - Studies add new findings to melanoma vaccines body of knowledge
Meningitis - Intimate kissing quadruples risk of meningitis in teenagers
Meningococcal Vaccine - Researchers present strategies to manage a cluster of meningococcal diseases
Molecular Diagnostics - Data highlighting the role of molecular diagnostics presented at major HIV/AIDS meeting
Multiple Myeloma Vaccine - Adenoviral-mediated gene transfer results in cytotoxicity of multiple myeloma cells
Multiple Sclerosis Therapy - Bone marrow transplant plus gene therapy ameliorates encephalomyelitis
Multiple Sclerosis Vaccine - Intradermal DNA vaccines encoding for T-cell receptors show promise for multiple sclerosis
Osteosarcomas - Use of cisplatin in metastatic osteosarcoma justified despite toxicity
Parkinson Disease - Recent findings in Parkinson disease provide new insights
Pediatric Cancer Therapy - Methodology presented for quantification of Act-D and VCR in pediatric cancers
Pertussis Vaccines - Researchers provide details of new studies and findings in the area of pertussis vaccines
Pharmacology - Efficacy of depsipeptide in childhood cancer models studied
Pneumococcal Disease - Antibodies to CbpA and Ply may protect children against pneumococcal colonization
Pneumococcal Vaccine - Study examined Streptococcus pneumoniae serotypes in Brazilian children
Pneumonia Vaccine - IgA modulates inflammatory responses in pneumonia in vitro model
Product Licensing - U.S. FDA licenses vaccine to protect infants against rotavirus infection
Prostate Cancer - Induction of apoptosis by 2-ME and paclitaxel in prostate cancer discussed
Prostate Cancer - Inosine 5'-monophosphate dehydrogenase inhibitors used to manage prostate cancer
Prostate Cancer - NaBu proposed as chemopreventive agent for prostate cancer
Prostate Cancer Vaccines - New findings in the area of prostate cancer vaccines described
Proteomics - Glutaredoxin 2 affinity tag for peptide and protein purification has been developed
Proteomics - Recovery of interferon alpha 2b from E. coli inclusion bodies has been optimized
Proteomics - Researchers optimized overexpression of glutamate mutase S component
Public Health - Pneumococcal vaccine in children decreases pneumococcal disease in HIV+ adults
Rotavirus Gastroenteritis - U.S. FDA approves Rotateq to prevent a leading cause of severe infant diarrhea
Rotavirus Vaccine - Review examines risks and benefits of rotavirus vaccines in Latin America
Smallpox Vaccine - Self-assessment of skin reaction is valid after smallpox vaccination
Soft Tissue Sarcomas - ET-743 proposed as novel agent with activity in soft tissue sarcomas
Staphylococcus Vaccine - Protein A triggers supraclonal B-cell responses upon Staphylococcus infection
Tick-Borne Disease - Boophilus microplus yolk pro-cathepsin shows promise for anti-tick vaccines
Toxoplasmosis Vaccine - Study characterized antibodies against Toxoplasma gondii MIC2 protein
Transplant Medicine - Article examines immunity for tumors and microbes after autotransplantation
Tuberculosis Diagnosis - Researchers publish new studies and findings in the area of tuberculosis diagnosis
Tuberculosis Vaccines - Recent studies add new data to tuberculosis vaccines research
Tuberculosis Vaccines - Texas, Brazilian scientists collaborate on TB vaccine
Typhus Vaccines - Studies advance knowledge in typhus vaccines research
Vaccine Adjuvants - CpG oligodeoxynucleotides function as effective adjuvant in aged mice
Vaccine Adjuvants - CpG-rich DNA suppresses T cell immunity via induction of IDO
Vaccine Delivery - Lipid emulsions increase transgene expression in hepatocytes after adenoviral transfer
Vaccine Development - Method to generate antibody against human protein SNEV has been developed
Vaccine Development - Phase I shows escalating doses of S. epidermidis and S. aureus vaccines are well-tolerated
Vaccine Efficacy - Inserting antigenic protein in flagellin improves Th1 immune response
Vaccines Vector - Researchers' work adds to vaccines vector body of knowledge
Vector Development - Binary AdEasy vector systems use Tet-regulated transgene expression
Vector Development - Findings describe new data in vector development research
Vector Development - High expression levels of alpha 1-antitrypsin are mediated by adeno-associated virus
Vector Development - New findings in the area of vector development described
Vector Development - New findings in vector development described
Virology - Genital human papillomavirus infection in men is focus of review
Virology - Study analyzed human respiratory syncytial virus phosphoprotein
Virology - Study examined genetic stability of dengue vaccine candidates
Virology - Study investigated porcine reproductive and respiratory syndrome virus vaccine
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