Allergy & Immunology
T-cell reaction indicates response to Th1-adjuvanted allergy vaccine
Published in Vaccine Weekly, March 8th, 2006
"Specific immunotherapy (SIT) is believed to modulate CD4+ T-helper cells. In order to improve safety, SIT vaccines are often formulated with allergoids (chemically modified allergens). Interaction between T-cells and allergoids is necessary to influence cellular cytokine expression. There have been few reports on identification the early cellular effects of SIT," scientists in the United States report.
"Patients allergic to grass and/or mugwort pollen (n=21) were treated with a four-shot allergy vaccine (Pollinex Quattro) containing appropriate...
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Source: Vaccine Weekly (2006-03-08)
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