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Smallpox Vaccine

Smallpox vaccination may be better at inner arm site than outer arm

Published in Vaccine Weekly, March 15th, 2006

The inner upper arm may be a better site for smallpox vaccination compared to the outer arm.

Scientists in the United States report, "Current recommendations direct health care providers to administer smallpox vaccine to the upper outer arm. However, concerns about cosmetically bothersome scarring, accidental contact transmission, interference by body tattoos, and even malignant transformation suggest evaluation of alternate vaccination sites is warranted."

"We randomized 20 vaccinia-naive adults to undergo smallpox vaccination on the outer (n=10) or inner (n=10) upper arm. Evaluations included major reaction ('take') rates and vaccination site...

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