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Tuberculosis Vaccines

Researchers report details of new studies and findings in the area of tuberculosis vaccines

Published in Vaccine Weekly, March 15th, 2006

Tuberculosis vaccines data are the focus of recent research from India and the United States.

Study 1: DNA vaccines against tuberculosis elicit efficient, protective immune responses.

According to recent research from India, "DNA vaccination is an effective method for elicitation of strong humoral as well as cellular immune responses. DNA vaccines expressing mycobacterial antigens ESAT-6 (Rv3875), alpha-crystallin (Rv2031c), and superoxide dismutase A (Rv3846) were evaluated for their immune responses in BALB/c mice and protective efficacy in guinea pigs."

"Immunization of mice with the DNA vaccines expressing superoxide dismutase...

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