Published in Vaccine Weekly, March 15th, 2006
According to a study from England, "The immunogenicity of viral DNA vectors is an important problem for gene therapy. The use of peptide motifs for gene delivery would largely overcome this problem, and provide a simple, safe and powerful approach for non-viral gene therapy. We explored the functional properties of two motifs: the (Lys)16 motif (for binding and condensing DNA and probably also nuclear, translocation of plasmids) and the fusogenic peptide motif of influenza virus (for acid-dependent...
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