Immunology

Sexual differences in immune response appear at puberty

Published in Vaccine Weekly, March 15th, 2006

The differences in the male and female immune responses, which make females more prone to autoimmune disease and males more subject to infections, are established during puberty.

In a study published February 22, 2006, in the open-access journal BMC Immunology (www.biomedcentral.com), researchers identified one of the mechanisms responsible for the difference in immune response between male and female mice. They show that this sexual disparity is established during puberty and is influenced by sex hormones.

These findings have implications for studies of autoimmunity, transplantation, and vaccination.

Kanneboyina Nagaraju...

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Source: Vaccine Weekly (2006-03-15)

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