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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . March 22nd, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Breast Cancer Vaccine - Breast cancer prognostic information is aided by monocyte chemotactic protein-1

Chlamydia Vaccine -  Chlamydia protection is better delivered by intranasal than transcutaneous vaccine

Escherichia Coli Vaccine -  E. coli O157O-specific vaccine is safe and immunogenic in children

Rotavirus Vaccine - Economics of rotavirus gastroenteritis and vaccine in Europe are focus of review

Tuberculosis Vaccine - Tuberculosis vaccine efficacy is affected by BCG strain and delivery route

Amebiasis Vaccine - Amebiasis vaccine is developed that blocks adherence

Apoptosis - Apoptosis of primary neurons is inhibited by varicella-zoster virus ORF63

Avian Influenza - Positive pre-IND meeting with U.S. FDA for avian flu vaccine completed by Generex

Breast Cancer - Breast cancer treated by possible antimetastatic formylated hexapeptide ligand

Breast Cancer - Breast cancer treated with combination of oral vinorelbine and capecitabine

Breast Cancer - MCF-7 breast cancer cell growth inhibited by Antrodia camphorata

Breast Cancer - Metastatic breast cancer treated by combination of pemetrexed and gemcitabine

Breast Cancer Vaccine - Breast cancer tumors frequently express cancer testis genes

Breast Cancer Vaccine - IL-12 and GM-CSF microsphere therapy eradicates tumors but does not provide long-term cure

Cancer Therapy - Bone metastasis is prevented by a selective cyclooxygenase-2 inhibitor

Cancer Therapy - Cancer cell growth inhibited by digitoxin

Cancer Vaccine - Antitumor activity in human lymphocytes is triggered by vaccine

Cancer Vaccine - Chaperone-rich cell lysates are good antigen source for anticancer vaccines

Cancer Vaccine - Contract arrangement announced for cGMP production of GRNVAC1 for clinical trials

Cancer Vaccine - For gene therapy of cholangiocarcinoma, tumor-specific promoters have been identified

Cancer Vaccine - Mouse hepatitis coronavirus is targeted to human epidermal growth factor receptor

Cancer Vaccine - NY-ESO-1 epitopes recognized by CD4+ T cells and presented by HLA-DQ B1 03011 have been identified

Cancer Vaccine - SOCS1 restricts dendritic cells' ability to induce antitumor immunity

Cancer Vaccine - Vaccine induces response against carcinoembryonic antigen in patients with metastases

Cancer Vaccines - Recent findings illuminate research in cancer vaccines

Cancer Vaccines - Researchers report details of new studies and findings in the area of cancer vaccines

Carcinogenesis - Antitumor resistance activation in mice was focus of research

Cervical Cancer Vaccine - Human papillomavirus-16 vaccine prevents cervical intraepithelial neoplasia

Chemotherapy - New findings in chemotherapy described

Clinical Trials - Norwood Abbey commences phase II trial of Lupron Depot in autologous bone marrow transplants

Colorectal Cancer - Colorectal cancer patients preferred oral to intravenous therapy

Complementary & Alternative Medicine - Degraded lambda-carrageenan could add antitumor activities of 5-Fu

Complementary & Alternative Medicine - New class of CDK2 inhibitors developed

Cytomegalovirus - Researchers describe findings in cytomegalovirus studies

DNA Vaccine - Interleukin-18 enhances Th1 immunity and tumor protection of a DNA vaccine

Dengue Fever - Dengue antigen developed

Drug Delivery - Intramuscular delivery methods for DNA vaccine in primate model were compared

Drug Development - Allergy Therapeutics commences sublingual allergy vaccine trial

Drug Development - Alloreactivity of dendritic cells is attenuated with microspheres and plasmid encoding IL-10

Drug Development - Biodegradable microspheres prolong antigen presentation by macrophages

Drug Development - Biotech firms seek pre-qualification from World Health Organization

Drug Development - Combination of porphyrins and DNA-alkylation agents described

Drug Development - DTH-inducing proteins from cDNA library have been identified

Drug Development - Dendrons with spermine surface groups are building blocks for nonviral vectors

Drug Development - Fluorescent phorboxazole A analog developed

Drug Development - Pharmacogenomics added to development of new marine-derived anticancer agents

Drug Development - Vaccinia virus Ankara multiplies in rat IEC-6 cells

Ebola Vaccine - Ebola vaccine with Vical technology produces immune responses in trial volunteers

Epidemiology - Measles incidence remains high in three Turkish cities

Epidemiology - Measles outbreak case-fatality rate is reported from Niger

Epidemiology - Measles outbreak prevention requires very high vaccine coverage in densely populated areas

Flavivirus Vaccine - West Nile virus antibodies prevent lethal infection through Fc gamma

Gene Therapy - Gene delivery is provided by repeated administration of adenovector

Gene Therapy - Gene delivery to respiratory epithelial cells is enhanced by serum albumin

Gene Therapy - Phenylketonuria gene expression profile is reversed by gene therapy

HIV/AIDS Research - Tanox research reaffirms tropism independence of TNX-355 for HIV

HIV/AIDS Vaccine - Antibody responses elicited by HIV glycoproteins are characterized

HIV/AIDS Vaccine - HIV therapeutic vaccination is focus of review

HIV/AIDS Vaccine - International AIDS Vaccine Initiative brings new science and technology to the poor

HIV/AIDS Vaccines - Recent findings illuminate research in HIV/AIDS vaccines

HIV/AIDS Vaccines - Recent studies add new data to HIV/AIDS vaccines research

HIV/AIDS Vaccines - Researchers describe findings in HIV/AIDS vaccines studies

HIV/AIDS Vaccines - Researchers report details of new studies and findings in the area of HIV/AIDS vaccines

Head & Neck Cancer - Vaccinia virus expressing IL-2 elicits immunity in head and neck cancer model

Hepatitis A Virus - CD4 count and gender predicts response to HAV vaccine in HIV-positive patients

Herpes Vaccine - Gamma herpesvirus 68 gene 50 null mutant fails to protect against wild-type challenge

Herpes Vaccine - Herpes simplex virus ocular infection is prevented by T cell chimeric epitopes

Human Metapneumovirus - Chimeric recombinant human metapneumovirus immunogenic and protective

Human Papillomavirus Vaccine - HPV-16 L1 virus-like particles are produced from Lactobacillus casei cells

Immunization - Vaccination medicine requires trust between medical practitioners and parents

Immunizations - Call for pertussis vaccination for healthcare workers endorsed by NFID

Immunology - New research in the area of immunology detailed

Immunotherapy - Dendritic cells are regulated by physiologically relevant thermal stress

Immunotherapy - Heat shock proteins HSP70 and GP96 are focus of review

Immunotherapy - Immune responses are modified by vaccination with lipiodol-siRNA

Immunotherapy - In experimental glioma, interstitial transfer factor is effective adjuvant immunotherapy

Immunotherapy - Transfection with cytokine may have limited long-term effectiveness

Immunotherapy - U.S. CDC committee recommends inclusion of Rotateq in Vaccines for Children Program

Infectious Diseases - Pneumococci with mef and erm macrolide resistance determinants is reported in an American city

Influenza - Influenza A burden underestimated in children and infants

Influenza Vaccine - Influenza nucleoprotein C terminus promotes HLA class I presentation

Influenza Vaccine - Proteosome-influenza vaccine induces influenza antibodies in humans

Information Technology - International AIDS vaccine R&D program selects enterprise timekeeping software

Leukemia - Apoptosis of leukemia cells induced by mycotoxin citrinin

Lung Cancer - First-line treatment regimens for elderly patients with lung cancer compared

Lung Cancer - Lung cancer suppressed by SC-560

Medulloblastomas - Medulloblastoma can be treated by fenretinide

Meningitis Vaccines - Researchers' findings advance meningitis vaccines research

Mergers & Acquisitions - MedMira completes acquisition of SensorChem

Mesothelioma - Mesothelioma patients treated early with chemotherapy had survival advantage

Multiple Myeloma - Multiple myeloma treated with bendamustine and prednisone

Newcastle Disease - Recombinant Newcastle disease virus vector protects against respiratory syncytial virus

Ovarian Cancer - Ovarian cancer inhibited by 9-methoxy-2-methylellipticinium acetate

Ovarian Cancer - Ovarian cancer treated by abraxane

Ovarian Cancer - Ovarian cancer treated by weekly dosing of irinotecan

Pediatric Vaccine - Hepatitis A vaccination was successfully targeted to high-risk children

Pediatrics HIV/AIDS Risk Factors - Infants perinatally infected with HIV at risk from BCG vaccination

Personnel - Point Therapeutics adds Charles Dinarello and Antonio Grillo-Lopez as advisors

Pertussis Vaccine -  B. pertussis attachment to respiratory cells is impaired by fimbriae-specific antibodies

Product Licensing - MNLpharma announces license agreement with Avexa to develop compounds to treat HIV/AIDS

Prostate Cancer - Apoptosis in hormone-resistant prostate cancer was induced by Alisol B acetate

Prostate Cancer - Unfolded protein response enhanced anticancer activity of selenium in prostate cancer

Prostate Cancer Vaccine - In prostate cancer, CD1c+ blood dendritic cells provide vaccine delivery

Prostate Cancer Vaccine - In prostate cancer, nitroreductase therapy increases antitumor immunity

Rhadinovirus - Rhadinovirus antibody-mediated neutralization was quantitated by recombinant virus

Rotavirus - Children's Hospital of Philadelphia includes rotavirus vaccine in infant immunization schedule

Rotavirus Vaccine - Rotavirus vaccine clinical trials in Europe are focus of review

SARS Vaccines - Research add new data to SARS vaccines body of knowledge

Salmonella Vaccine -  Salmonella porins induce lifelong specific bactericidal antibody memory

Smallpox Vaccine - Vaccinia virus-induced cell motility requires F11L-mediated inhibition of RhoA signaling

Smallpox Vaccines - Findings describe new data in smallpox vaccines research

Smallpox Vaccines - New findings in smallpox vaccines described

Smallpox Vaccines - Reports describe recent advances in smallpox vaccines research

Smallpox Vaccines - Studies describe new findings in smallpox vaccines research

Squamous Cell Carcinoma - Oral squamous cell carcinoma immune potency is promoted by CD40

Toxoplasmosis Vaccine - Toxoplasmosis vaccine provides partial cross-protection against congenital transmission

Tuberculosis Vaccine - Tuberculin skin testing is useful for infection control

Tuberculosis Vaccine - Tuberculosis is protected against by apoptotic vesicles that cross-prime CD8 T cells

Tularemia Vaccines - Researchers describe findings in tularemia vaccines studies

Uveitis Vaccine - Uveitis is protected against by gene transfer of S-antigen immunoglobulin fusion protein

Vaccines Adjuvant - Findings advance knowledge in vaccines adjuvant research

Vaccines Delivery - Studies add new findings to vaccines delivery body of knowledge

Vaccines Vector - Reports describe recent advances in vaccines vector research

Virology - Feline immunodeficiency virus restriction by Ref1, Lv1, and TRIM5 alpha proteins is examined

Virology - Varicella seroprevalence in French population is reported

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