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Smallpox Vaccines

Studies describe new findings in smallpox vaccines research

Published in Vaccine Weekly, March 22nd, 2006

Investigators in the United States have published new smallpox vaccines data.

Study 1: Scientists characterize vaccinia virus (Dryvax) antigens recognized by vaccinia immune globulin in a recent issue of the journal Virology.

According to a study from the United States, "Using vaccinia immune globulin (VIG), a high-titer antibody preparation from immunized subjects, we demonstrate that the humoral immune response in humans is directed against numerous antigens in the Dryvax vaccine strain. Western blot and immunoprecipitation analyses revealed highly antigenic proteins associated with both the extracellular enveloped virus and intracellular...

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