Cancer Therapy
Cancer cell growth inhibited by digitoxin
Published in Vaccine Weekly, March 22nd, 2006
According to recent research from Spain, "The cardiac glycosides digitoxin (1) and digoxin (3) have been used in cardiac diseases for many years. During this time several reports have suggested the possible use of digitalis in medical oncology."
"Several analogues of digitoxin (1) were evaluated for growth inhibition activity in three human cancer cell lines; this study showed that digitoxin (1) was the most active compound and revealed some structural features that may play a role in the growth inhibition activity of these drugs. The IC50 values for 1 (3-33 nM) were within or below the...
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Source: Vaccine Weekly (2006-03-22)
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