HIV/AIDS Vaccines
Researchers report details of new studies and findings in the area of HIV/AIDS vaccines
Published in Vaccine Weekly, March 22nd, 2006
Study 1: Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces protective immunity against HIV.
According to recent research from Japan and the United States, "Immunization involving a DNA vaccine prime followed by an adenovirus type 5 (Ad5) boost elicited a protective immune response against SHIV challenge in monkeys. However, the hepatocellular tropism of Ad5 limits the safety of this viral vector. This study examines the safety and immunogenicity of a replication-defective chimeric Ad5...
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Source: Vaccine Weekly (2006-03-22)
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