Drug Development
Synthesis and antitumor activity of platinum acetonimine complexes described
Published in Vaccine Weekly, March 29th, 2006
"The cis- and trans-dichloro- and diiodo-platinum(II) complexes containing two acetonimines (cis- and trans-[PtX2 {HN=C(CH3 )2 }2 ] 1 and 2 for X=Cl and 1' and 2' for X=1, respectively) or one acetonimine and one ammine (cis- and trans-[PtX2 (NH3 ){HN=C(CH3 )2 }], 3 and 4 for X=Cl and 3' and 4' for X=1, respectively) have been prepared from platinum-ammine precursors by condensation with acetone," scientists writing in the Journal of Medicinal Chemistry reported.
"Except...
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Source: Vaccine Weekly (2006-03-29)
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