Published in Vaccine Weekly, March 29th, 2006
According to a recent report published in the journal Virology, "The classical viral vaccine approaches using inactivated virus or live-attenuated virus have not been successful for some viruses, such as human immunodeficiency virus or herpes simplex virus. Therefore, new types of vaccines are needed to combat these infections."
"Replication-defective mutant viruses are defective for one or more functions that are essential for viral genome replication...
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