SARS Vaccine
Anti-SARS-CoV immunity is induced by a novel CpG oligodeoxynucleotide
Published in Vaccine Weekly, April 19th, 2006
"To develop CpG ODNs based therapy for prevention and treatment of SARS, we selected a novel CpG ODN (BW001), which displays B-type CpG ODN structure feature at the 5' and A-type CpG ODN structure feature at the 3' and tested for its anti-SARS-CoV activity," wrote M.S. Bao and colleagues of Jilin University.
"We found that the supernatants of human PBMCs stimulated by BW001 significantly protected Vero cells from SARS-CoV infection. BW001 could stimulate human PBMCs and pDCs...
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Source: Vaccine Weekly (2006-04-19)
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