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Avian Influenza Vaccine

Adenovirus-based vaccine protects against lethal H5N1 avian influenza

Published in Vaccine Weekly, April 26th, 2006

Adenovirus-based immunization protected mice and poultry from lethal H5N1 avian influenza virus.

According to recent research published in the Journal of Virology, "The recent emergence of highly pathogenic avian influenza virus (HPAI) strains in poultry and their subsequent transmission to humans in Southeast Asia have raised concerns about the potential pandemic spread of lethal disease. In this paper we describe the development and testing of an adenovirus-based influenza A virus vaccine directed against the hemagglutinin (RA) protein of the A/Vietnam/1203/2004 (H5N1) (VN/1203/04) strain isolated during the lethal human outbreak in Vietnam from 2003 to...

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