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Foot-and-Mouth Disease

Method detects cell-mediated immune responses to foot-and-mouth disease virus

Published in Vaccine Weekly, April 26th, 2006

Scientists have developed a rapid method to detect cell-mediated immune responses to foot-and-mouth disease virus (FMDV) that correlates with protection after vaccination.

According to recent research from England, "Studies were performed to determine whether a rapid method to detect cell-mediated immune responses to foot-and-mouth disease virus (FMDV) could be used either as a diagnostic test or provide a correlate of protection in animals post-vaccination. Using protocols based on the BOVIGAM assay for tuberculosis, whole blood samples from FMDV vaccinated or control animals, before and after challenge infection, were stimulated overnight with inactivated FMDV...

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