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HIV/AIDS Vaccine

Group M-based HIV-1 Gag peptides frequently targeted by T cells in chronic infection

Published in Vaccine Weekly, April 26th, 2006

Group M-based HIV-1 Gag peptides are frequently targeted by T cells in chronic infection.

According to recent research published in the journal AIDS, "The enormous sequence diversity of HIV-1 has been a major obstacle in the development of a globally useful vaccine for AIDS.

"The consensus and ancestral sequence-based immunogens minimize the genetic distance between contemporary isolates and vaccine strains. Hence these sequences may be promising candidates for HIV vaccines or serve as a universal reagent set for evaluating Gag-specific responses."

"In this study, wrote A. Bansal and colleagues at the University of Alabama,...

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