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Allergy & Immunology

Recombinant allergens, hypoallergenic derivatives are potential type I allergy therapy

Published in Vaccine Weekly, April 26th, 2006

Recombinant allergens and hypoallergenic derivatives may be used for the treatment of type I allergies.

"Currently, diagnosis of type I allergy is performed using crude allergen extracts, which allow the identification of the allergen-containing source responsible for type I allergic symptoms (e. g., allergic rhino-conjunctivitis, asthma) but not the disease-eliciting molecules. With the introduction of recombinant allergens produced by molecular biology techniques, a large panel of allergenic molecules has become available," scientists in Austria reported.

"The application of these recombinant allergens for in vitro tests has led to new forms of...

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