Vaccine Efficacy
Immune response of vaccinia virus vectors is enhanced by IFN-gamma or IL-12
Published in Vaccine Weekly, May 3rd, 2006
According to recent research published in the journal Virus Research, "Recombinants based on vaccinia virus vectors, especially on the highly attenuated modified vaccinia virus Ankara (MVA) strain, are now being tested in clinical trials for safety and immunogenicity, using prime/boost heterologous regimes of vaccination. Due to the limited replication capacity of MVA, it is necessary to develop procedures that can enhance the specific cellular immune responses to the recombinant antigen delivered by the MVA vector."
"In...
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Source: Vaccine Weekly (2006-05-03)
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