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Cancer Drugs



Bilirubin exhibited anti-cancer activity in human adenocarcinoma



May 10th, 2006

Bilirubin exhibited anti-cancer activity in human adenocarcinoma.

According to recent research published in the journal Biochemical and Biophysical Research Communications, "Anti-oxidants are essential for intracellular free radical scavenging, as free radicals are one of the causes for tumorigenesis. Our objective was to use bilirubin and investigate its action on human carcinoma cell lines."

"Bilirubin manifested as a prooxidant showing its cytopathic effect on TMK-1, showing growth inhibition close to 50%. Cell cycle analysis showed an arrest at G0/G1. Flow cytometry investigations with Red CC-1 showed an increase by more than 2 times...


Source: Vaccine Weekly (2006-05-10)

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